In Acute Cholecystitis, which of the following lab changes is typically NOT observed?

In acute cholecystitis, the primary concern is inflammation of the gallbladder, often due to obstruction by gallstones. The laboratory findings that are typically associated with this condition help in assessing the inflammation and potential complications.

Elevated bilirubin can occur in acute cholecystitis, particularly if there is associated biliary obstruction, which can cause increased levels of both direct and indirect bilirubin in the serum. Elevated liver enzymes are also commonly seen, especially if there is a significant obstruction to the bile duct that can affect liver function. A high white blood cell count indicates an inflammatory response, which is frequently observed in acute cholecystitis due to the infection or irritation of the gallbladder.

In contrast, elevated creatinine is generally not observed in cases of acute cholecystitis. Creatinine is a marker of kidney function, and while indirect effects of severe infection or dehydration can lead to elevated creatinine levels, it is not a typical finding specific to cholecystitis. Therefore, elevated creatinine is the lab change that is usually not associated with acute cholecystitis.