Significant hyperglycemia and ketoacidosis due to lack of insulin primarily apply to which type of diabetes?

Significant hyperglycemia and ketoacidosis due to a lack of insulin primarily applies to Type I Diabetes. This type of diabetes is characterized by the autoimmune destruction of pancreatic beta cells, which are responsible for producing insulin. As a result, individuals with Type I Diabetes have little to no insulin in their bodies.

When insulin is deficient, the body cannot effectively utilize glucose for energy, leading to an accumulation of glucose in the bloodstream (hyperglycemia). Additionally, in the absence of insulin, the body begins to break down fats for energy, leading to the production of ketones, which can result in ketoacidosis – a serious metabolic condition characterized by high levels of ketone bodies, acidosis, and electrolyte imbalances. This condition requires prompt medical attention to prevent severe complications.

Other types of diabetes can have different characteristics; for example, Type II Diabetes typically involves insulin resistance, where the body still produces some insulin but cannot use it effectively. Gestational Diabetes occurs during pregnancy and often resolves after childbirth, while LADA (Latent Autoimmune Diabetes in Adults) may present more like Type II in its early stages but eventually progresses to an insulin-deficient state similar to Type I. However, it is the immediate and severe insulin deficiency seen in