Which medication is appropriate for treating a recurrent duodenal ulcer?

When treating a recurrent duodenal ulcer, the most appropriate medication is antimicrobial therapy, particularly when the underlying cause is related to an infection with Helicobacter pylori (H. pylori). H. pylori infection is a significant contributor to the development of peptic ulcers, including duodenal ulcers.

In cases of recurrent ulcers, eradicating H. pylori infection can significantly reduce the likelihood of ulcer recurrence. Antimicrobials such as amoxicillin, clarithromycin, and metronidazole are often used in combination therapies aimed at successfully treating the infection. It is essential to ensure a complete and effective eradication of H. pylori to promote healing and prevent future occurrences of the ulcer.

Other treatment options, while they have their roles in ulcer management, do not directly address the root cause of recurrent duodenal ulcers related to H. pylori. Proton pump inhibitors and H2 receptor antagonists are useful for reducing gastric acid secretion and promoting healing but do not target the underlying infection. Antacids may provide symptomatic relief but are not a curative treatment for the infection itself. Therefore, for recurrent duodenal ulcers associated with H. pylori, antimicrobial therapy is the most appropriate choice.